Cefuroxime is used in the treatment of bacterial infections. It is used for the treatment of bacterial infections of urinary tract, skin and soft tissue, blood, and lungs (pneumonia). It is also used to prevent infections after surgery. Cefuroxime is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive. This is a second-generation cephalosporin antibiotic used to treat and prevent a number of bacterial infections. These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease.